This study contains a list of other medicines where there is insufficient information or conflicting data is to support or refute its use for prevention of migraines.
According to researchers, about 38% of victims who suffer from migraine preventive treatment benefit, which can reduce the frequency or intensity of attacks, but most do not use it. Only about a third of patients are likely to use some kind of preventive treatment for migraine.
One case cited is that of Gina Gjorvad, he began taking prescription medications at age 11. These drugs did little to ease their pain. As an adult, his doctor recommended nortriptyline daily as a preventive treatment, but also helped to significantly reduce the frequency or severity of migraine attacks. Later his doctor recommended topiramate, which halved the frequency of attacks, which left even with 8 or 10 migraine attacks per month. It was only when another neurologist advised him to increase the dosage, the frequency of attacks was reduced to about three per month.
The above is typical of migraine sufferers. They usually start taking painkillers that do not require a prescription, and in many cases are unnecessary or are not sufficient to relieve pain or frequency of attacks. If you suffer from migraine, and you take the medication not working for you, consult your doctor. You may be taking one that is not right for your problem, or you take it in doses too low to be effective. But do not change medicine or you increase the dose on your own. Only your doctor can decide which preventive treatment for you to prevent or make less severe and less frequent migraine attacks. Remember, find the medication and dosage that work to prevent and treat migraines is possible.